Effect of Thyme Essential Oil On Drug-Resistant Pseudomonas Isolated From Cystic Fibrosis Patients

Abstract

Pseudomonas aeruginosa is a gram-negative bacterium that is abundant in a variety of moist environments, such as soil and water, and can adapt to many other environments. As an opportunistic pathogen, Pseudomonas aeruginosa has been identified as one of the most important hospital pathogens in recent years. It is highly resistant to a variety of antibiotics and antibiotics, and is the main problem of bacterial treatment in important wards of hospitals such as burns and intensive care. In these patients, skin defense is lost. Burn wound healing is a complex process that involves an early burst of energy depletion and cell necrosis, followed by an inflammatory phase, cell death, granulation tissue formation, matrix formation, and collagen rearrangement. Bacterial or antioxidant activity is a good candidate for wound healing. The purpose of this study was to evaluate the effect of thyme essential oil on drug-resistant Pseudomonas isolated from cystic fibrosis patients. According to the findings of this study, thyme essential oil has significant antimicrobial activity, and its impact on clinical and drug-resistant Pseudomonas aeruginosa can lead to failure of bacterial resistance and accelerate its treatment in clinical wards.