Study on the Performance of Calcium - or Non-Calcium - Based Phosphate Binder in the Treatment of Hyperparathyroidism Secondary to Chronic Renal Failure

Abstract

Secondary hyperparathyroidism is one of the most prevalent complications in the advancement of CKD which specifically appears when glomerular filtration rate decreases to a level lower than 80 cc per minute for a period of longer than three months. Physicians in charge of CKD and pre-dialysis patients should be attentive to investigate and correct all the conditions that cause the compensating increase of parathyroid hormone (PTH). In this respect the first action is to correct hypophosphatemia, which at first stages is corrected through monitored diet, and then with calcium- or non-calcium-based phosphate binders.