Alligators and Frogs: A More Pharmacovigilant Source of Drugs for Multiple Resistant Microorganisms and Other Bodily Diseases

Abstract

Frogs and alligators promise to provide an alternative source of newer drugs in the community of drug discovers and developers. It is of a great importance to note that some of the alkaloids found in herbal plants can also be found in animals, or at least similar groups of compounds. There is therefore need to concert efforts in research on animal venoms, secretions and other peptides that have the potential to develop more pharmacovigilant drugs against multi drug resistant microorganisms and other bodily disorders. The effort are highly required in both drug structure activity relationships as well as structure property relationships in order to determine bioavailability predictions at earlier stages of drug discovery. Besides pharmacognosy, this paper urges researchers to also invest in animal secretions for potential drug development.